COX-1

MGI MGI:97798

Expression Profile

  MGI  SwissProt  PhenOntology  Affy  Unigene  RefSeq  LocusLink  GeneOntology  

MGI  Top

ID: MGI:97798
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2

SwissProt  Top

ID: PGH2_MOUSE
Accession: Q05769
Name: PTGS2
Species: Mus musculus
Protein: Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase -2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).
Functions: MAY HAVE A ROLE AS A MAJOR MEDIATOR OF INFLAMMATION AND/OR A ROLE FOR PROSTANOID SIGNALING IN ACTIVITY-DEPENDENT PLASTICITY.

PhenOntology  Top

ID: MP:0001790
Name: immune system: response/function abnormalities
ID: MP:0001790
Name: immune system: response/function abnormalities
ID: MP:0002081
Name: survival: perinatal lethality
ID: MP:0002083
Name: survival: premature death
ID: MP:0002121
Name: metabolism: other metabolic defect
ID: MP:0002127
Name: heart/cardiovascular system: dysmorphology
ID: MP:0002135
Name: kidney/renal system: dysmorphology
ID: MP:0002141
Name: digestive system: dysmorphology
ID: MP:0002160
Name: reproductive system: dysmorphology
ID: MP:0002161
Name: reproductive system: fertility/fecundity anomalies

Affy  Top

ID: 104647_at
ID: 1417262_at
ID: 1417263_at
ID: m64291_s_at
ID: Msa.722.0_i_at
ID: X98792_rc_at

Unigene  Top

ID: Mm.3137
Title: prostaglandin-endoperoxide synthase 2
Gene: Ptgs2
Cytoband: 1 76.2 cM

RefSeq  Top

ID: NM_011198

LocusLink  Top

ID: 19225
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2

GeneOntology  Top

ID: 0001516
Name: prostaglandin biosynthesis
ID: 0004601
Name: peroxidase activity
ID: 0004666
Name: prostaglandin-endoperoxide synthase activity
ID: 0005615
Name: extracellular space
ID: 0005634
Name: nucleus
ID: 0005737
Name: cytoplasm
ID: 0008217
Name: regulation of blood pressure
ID: 0016020
Name: membrane
ID: 0016491
Name: oxidoreductase activity
ID: 0016702
Name: oxidoreductase activity\, acting on single donors with incorporation of molecular oxygen\, incorporation of two atoms of oxygen

Remarks  Top

Expression Dataset (gene specific):
   m64291_s_at: NULL
   Msa.722.0_i_at: NULL
   X98792_rc_at: NULL

Expression Profile  Top

Gene ID m64291_s_at Msa.722.0_i_at X98792_rc_at
Quiescence-Term-18
HOPACH Clusters
Quiescence-Term-Post
Quiescence-Term-14
Quiescence-T-P 2fold
Postpartum
non-pregnant avg 67.48 58.18 73.34
14days avg 59.98 57 67.55
14days fold -1.12 -1.02 -1.09
16days avg 70.26 56.36 68.93
16days fold 1.04 -1.03 -1.06
16v14 fold 1.17 -1.01 1.02
17days avg 71.39 57.51 72.58
17days fold 1.06 -1.01 -1.01
17v16 fold 1.02 1.02 1.05
18days avg 68.05 56.43 73.61
18days fold 1.01 -1.03 1
18v14 fold 1.13 -1.01 1.09
18v16 fold -1.03 1 1.07
18v17 fold -1.05 -1.02 1.01
6hrs avg 67.99 56.81 69.28
6hrs fold 1.01 -1.02 -1.06
6v18 fold -1 1.01 -1.06
24hrs avg 67.74 60.45 68.46
24hrs fold 1 1.04 -1.07
24v18 fold -1 1.07 -1.08
24v6 fold -1 1.06 -1.01
GenBank M64291 M88242 X98792
GenMAPP ID Q05769 Q05769 Q05769
Gene_Symbol Ptgs2 Ptgs2 Ptgs2
MapLocation 1 76.2 cM 1 76.2 cM 1 76.2 cM
f-rawp 0.267 0.7175 0.4336
f-adjp 1 1 1
gestation >20p 0 0 0
post>20p 0 0 0
gestation<-20p 0 0 0
post<-20p 0 0 0
Sum all 0 0 0
np fold-log 0 0 0
14d fold-log -0.17 -0.03 -0.12
16d fold-log 0.06 -0.05 -0.09
17d fold-log 0.08 -0.02 -0.02
18d fold-log 0.01 -0.04 0.01
6hrs fold-log 0.01 -0.03 -0.08
24hrs fold-log 0.01 0.06 -0.1
final cluster NULL NULL NULL
main cluster NULL NULL NULL
2nd level cluster NULL NULL NULL
main/medoid order NULL NULL NULL
Mediod NULL NULL NULL
total in cluster NULL NULL NULL
final order NULL NULL NULL
HOPACH Pattern NULL NULL NULL
Abs-main cluster NULL NULL NULL
Abs final order NULL NULL NULL
Abs-Pattern NULL NULL NULL
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