COX-1

MGI MGI:97797

Expression Profile

  MGI  SwissProt  PhenOntology  Affy  Unigene  RefSeq  LocusLink  GeneOntology  

MGI  Top

ID: MGI:97797
Symbol: Ptgs1
Name: prostaglandin-endoperoxide synthase 1

SwissProt  Top

ID: PGH1_MOUSE
Accession: P22437
Name: PTGS1
Species: Mus musculus
Protein: Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase -1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).
Functions: May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells.
ID: Q8CIL6
Accession: Q8CIL6
Name: PTGS1
Species: Mus musculus
Protein: Similar to prostaglandin-endoperoxide synthase 1 (Fragment).

PhenOntology  Top

ID: MP:0001790
Name: immune system: response/function abnormalities
ID: MP:0002135
Name: kidney/renal system: dysmorphology
ID: MP:0002161
Name: reproductive system: fertility/fecundity anomalies
ID: MP:0002551
Name: hematology: abnormal blood coagulation

Affy  Top

ID: 1423414_at
ID: 1436448_a_at
ID: 161694_f_at
ID: 95597_at
ID: M34141_s_at

Unigene  Top

ID: Mm.2792
Title: prostaglandin-endoperoxide synthase 1
Gene: Ptgs1
Cytoband: 2 29.0 cM

RefSeq  Top

ID: NM_008969

LocusLink  Top

ID: 19224
Symbol: Ptgs1
Name: prostaglandin-endoperoxide synthase 1

GeneOntology  Top

ID: 0001516
Name: prostaglandin biosynthesis
ID: 0004601
Name: peroxidase activity
ID: 0004666
Name: prostaglandin-endoperoxide synthase activity
ID: 0005615
Name: extracellular space
ID: 0005634
Name: nucleus
ID: 0005737
Name: cytoplasm
ID: 0005792
Name: microsome
ID: 0008217
Name: regulation of blood pressure
ID: 0016020
Name: membrane
ID: 0016491
Name: oxidoreductase activity
ID: 0016702
Name: oxidoreductase activity\, acting on single donors with incorporation of molecular oxygen\, incorporation of two atoms of oxygen

Expression Profile  Top

Gene ID M34141_s_at
Quiescence-Term-18
HOPACH Clusters
Quiescence-Term-Post
Quiescence-Term-14
Quiescence-T-P 2fold
Postpartum
non-pregnant avg 217.76
14days avg 435.71
14days fold 2
16days avg 512.36
16days fold 2.35
16v14 fold 1.18
17days avg 461.64
17days fold 2.12
17v16 fold -1.11
18days avg 540.66
18days fold 2.48
18v14 fold 1.24
18v16 fold 1.06
18v17 fold 1.17
6hrs avg 197.92
6hrs fold -1.1
6v18 fold -2.73
24hrs avg 221.7
24hrs fold 1.02
24v18 fold -2.44
24v6 fold 1.12
GenBank M34141
GenMAPP ID P22437
Gene_Symbol Ptgs1
MapLocation 2 29.0 cM
f-rawp 0.0001
f-adjp 0.0217
gestation >20p 4
post>20p 0
gestation<-20p 0
post<-20p 0
Sum all 4
np fold-log 0
14d fold-log 1
16d fold-log 1.23
17d fold-log 1.08
18d fold-log 1.31
6hrs fold-log -0.14
24hrs fold-log 0.03
final cluster 7.10E+15
main cluster 71000000
2nd level cluster 71
main/medoid order 3604
Mediod no
total in cluster 183
final order 3546
HOPACH Pattern Up Quiescence
Abs-main cluster 25400
Abs final order 1461
Abs-Pattern NULL
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