CCNH

MGI MGI:1913921

Expression Profile

  MGI  SwissProt  Affy  Unigene  RefSeq  LocusLink  GeneOntology  

MGI  Top

ID: MGI:1913921
Symbol: Ccnh
Name: cyclin H

SwissProt  Top

ID: CYCH_MOUSE
Accession: Q61458, Q9CVJ0, Q9JHV7
Name: CCNH
Species: Mus musculus
Protein: Cyclin H.
Functions: Regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive carboxyl-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

Affy  Top

ID: 116360_at
ID: 1418584_at
ID: 1418585_at
ID: 1456293_s_at
ID: 162561_at
ID: Msa.31187.0_s_at

Unigene  Top

ID: Mm.18474
Title: cyclin H
Gene: Ccnh
Cytoband: 13 C3

RefSeq  Top

ID: NM_023243

LocusLink  Top

ID: 66671
Symbol: Ccnh
Name: cyclin H

GeneOntology  Top

ID: 0004693
Name: cyclin-dependent protein kinase activity
ID: 0005634
Name: nucleus
ID: 0006355
Name: regulation of transcription\, DNA-dependent
ID: 0007049
Name: cell cycle
ID: 0016301
Name: kinase activity
ID: 0016538
Name: cyclin-dependent protein kinase\, intrinsic regulator activity

Remarks  Top

GenMAPP MAPP: CCNH; cyclin H
Expression Dataset (gene specific):
   Msa.31187.0_s_at: NULL

Expression Profile  Top

Gene ID Msa.31187.0_s_at
Quiescence-Term-18
HOPACH Clusters
Quiescence-Term-Post
Quiescence-Term-14
Quiescence-T-P 2fold
Postpartum
non-pregnant avg 181.07
14days avg 192.22
14days fold 1.06
16days avg 197.83
16days fold 1.09
16v14 fold 1.03
17days avg 198.7
17days fold 1.1
17v16 fold 1
18days avg 197.89
18days fold 1.09
18v14 fold 1.03
18v16 fold 1
18v17 fold -1
6hrs avg 194.07
6hrs fold 1.07
6v18 fold -1.02
24hrs avg 165.41
24hrs fold -1.09
24v18 fold -1.2
24v6 fold -1.17
GenBank AA103644
GenMAPP ID Q61458
Gene_Symbol Ccnh
MapLocation 13 C3
f-rawp 0.8522
f-adjp 1
gestation >20p 0
post>20p 0
gestation<-20p 0
post<-20p 0
Sum all 0
np fold-log 0
14d fold-log 0.09
16d fold-log 0.13
17d fold-log 0.13
18d fold-log 0.13
6hrs fold-log 0.1
24hrs fold-log -0.13
final cluster NULL
main cluster NULL
2nd level cluster NULL
main/medoid order NULL
Mediod NULL
total in cluster NULL
final order NULL
HOPACH Pattern NULL
Abs-main cluster NULL
Abs final order NULL
Abs-Pattern NULL
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