MAP2K2

EntrezGene 5605

Expression Profile

  Affy  EMBL  Ensembl  EntrezGene  GeneOntology  HUGO  InterPro  OMIM  PDB  Pfam  RefSeq  UniGene  UniProt  

Affy  Top

ID: 1131_at
Chip: HC_G110 HG_U95Av2
ID: 202424_at
Chip: HG-Focus HG-U133_Plus_2
ID: 213487_at
Chip: HG-U133_Plus_2
ID: 213490_s_at
Chip: HG-U133_Plus_2
ID: 237878_at
Chip: HG-U133_Plus_2
ID: 32519_at
Chip: HG_U95Av2
ID: 58848_at
Chip: HG_U95C
ID: 70077_at
Chip: HG_U95D
ID: 76967_at
Chip: HG_U95E
ID: 80459_at
Chip: HG_U95E
ID: L11285_at
Chip: Hu6800

EMBL  Top

ID: BC000471
ID: BC018645
ID: BC067760
ID: BX538081
ID: L11285

Ensembl  Top

ID: ENSG00000126934
Symbol: MAP2K2
Description: Dual specificity mitogen-activated protein kinase kinase 2 (EC 2.7.1.-) (MAP kinase kinase 2) (MAPKK 2) (ERK activator kinase 2) (MAPK/ERK kinase 2) (MEK2). [Source:Uniprot/SWISSPROT;Acc:P36507]
Chromosome: 19

EntrezGene  Top

ID: 5605
Symbol: MAP2K2
Name: mitogen-activated protein kinase kinase 2

GeneOntology  Top

ID: 0000166
Name: nucleotide binding
ID: 0004674
Name: protein serine/threonine kinase activity
ID: 0004713
Name: protein-tyrosine kinase activity
ID: 0005524
Name: ATP binding
ID: 0005576
Name: extracellular region
ID: 0006468
Name: protein amino acid phosphorylation
ID: 0016740
Name: transferase activity

HUGO  Top

ID: MAP2K2

InterPro  Top

ID: IPR000719
Name: Prot_kinase
Description: Protein kinase
ID: IPR001245
Name: Tyr_pkinase
Description: Tyrosine protein kinase
ID: IPR001472
Name: NLS_BP
Description: Bipartite nuclear localization signal
ID: IPR008271
Name: Ser_thr_pkin_AS
Description: Serine/threonine protein kinase, active site

OMIM  Top

ID: 601263

PDB  Top

ID: 1S9I

Pfam  Top

ID: PF00069

RefSeq  Top

ID: NP_109587

UniGene  Top

ID: Hs.465627

UniProt  Top

ID: P36507
Symbol: MAP2K2
Name: MP2K2_HUMAN
ID: Q6NW23
Symbol: MAP2K2
ID: Q7Z370
Symbol: MAP2K2

Expression Profile  Top

Gene ID 202424_at 213490_s_at
H1-ESC percent exp
H2-ESC percent exp
H9-ESC percent exp
Lethality
symbol MAP2K2 MAP2K2
CardiacMyocytes    
Heart    
Heart_GSE3585_ 8.395994  
Heart_GSM4467 8.08427  
ESC-H1p_ 8.927095 6.134275
ESC-H9_ 9.587523 6.795109
ESC_derived-MSC    
ESC-H2 9.266513 6.674303
EBs-H2-14d    
hEBs-H2-5d 9.236574 5.451612
CardiacMyocytes-call 0 0
Heart-call 0 0
Heart_GSE3585-call 0.4223319 0
Heart_GSM4467-call 0.3402635 0
atrioventricular_node-call 0 0
ESC-H1-call 0.6102831 0.3544593
ESC-H2-call 0.7721578 0.5153841
ESC-H9-call 0.9645835 0.5603989
GPCR-sing ling-component    
GPCR    
Phenotype_full normal normal
Phenotype    
expressed P-call_max2 1 1
Notes    
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