EGFR

EntrezGene 1956

Expression Profile

  Affy  EMBL  Ensembl  EntrezGene  GeneOntology  HUGO  InterPro  OMIM  PDB  Pfam  RefSeq  UniGene  UniProt  

Affy  Top

ID: 1537_at
Chip: HC_G110 HG_U95Av2
ID: 1565483_at
Chip: HG-U133_Plus_2
ID: 1565484_x_at
Chip: HG-U133_Plus_2
ID: 201983_s_at
Chip: HG-U133_Plus_2
ID: 201984_s_at
Chip: HG-U133_Plus_2
ID: 210984_x_at
Chip: HG-U133_Plus_2
ID: 211550_at
Chip: HG-U133_Plus_2
ID: 211551_at
Chip: HG-Focus HG-U133_Plus_2
ID: 211607_x_at
Chip: HG-U133_Plus_2
ID: 224999_at
Chip: HG-U133_Plus_2
ID: 232541_at
Chip: HG-U133_Plus_2
ID: 237938_at
Chip: HG-U133_Plus_2
ID: 243327_at
Chip: HG-U133_Plus_2
ID: 37327_at
Chip: HG_U95Av2
ID: 44154_at
Chip: HG_U95B
ID: 45474_at
Chip: HG_U95B
ID: 55275_at
Chip: HG_U95B
ID: 58050_at
Chip: HG_U95C
ID: 65700_at
Chip: HG_U95C
ID: 66515_at
Chip: HG_U95C
ID: X00588_at
Chip: Hu6800

EMBL  Top

ID: AB209442
ID: AB221348
ID: AC073324
ID: AF125253
ID: AF125538
ID: AF125539
ID: AF277897
ID: AF288738
ID: AY588246
ID: AY698023
ID: AY698024
ID: M11234
ID: M38425
ID: U48722
ID: U48723
ID: U48724
ID: U48725
ID: U48726
ID: U48727
ID: U48728
ID: U48729
ID: U95089
ID: X00588
ID: X00663
ID: X06370

Ensembl  Top

ID: ENSG00000146648
Symbol: EGFR
Description: Epidermal growth factor receptor precursor (EC 2.7.1.112) (Receptor tyrosine-protein kinase ErbB-1). [Source:Uniprot/SWISSPROT;Acc:P00533]
Chromosome: 7

EntrezGene  Top

ID: 1956
Symbol: EGFR
Name: epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)

GeneOntology  Top

ID: 0000166
Name: nucleotide binding
ID: 0001503
Name: ossification
ID: 0003690
Name: double-stranded DNA binding
ID: 0004710
Name: MAP/ERK kinase kinase activity
ID: 0004872
Name: receptor activity
ID: 0005006
Name: epidermal growth factor receptor activity
ID: 0005515
Name: protein binding
ID: 0005524
Name: ATP binding
ID: 0005615
Name: extracellular space
ID: 0005634
Name: nucleus
ID: 0005768
Name: endosome
ID: 0005886
Name: plasma membrane
ID: 0006468
Name: protein amino acid phosphorylation
ID: 0006950
Name: response to stress
ID: 0007049
Name: cell cycle
ID: 0007173
Name: epidermal growth factor receptor signaling pathway
ID: 0007202
Name: phospholipase C activation
ID: 0008283
Name: cell proliferation
ID: 0016021
Name: integral to membrane
ID: 0016337
Name: cell-cell adhesion
ID: 0016740
Name: transferase activity
ID: 0030122
Name: AP-2 adaptor complex
ID: 0030235
Name: nitric-oxide synthase regulator activity
ID: 0030335
Name: positive regulation of cell migration
ID: 0042327
Name: positive regulation of phosphorylation
ID: 0043006
Name: calcium-dependent phospholipase A2 activation
ID: 0045429
Name: positive regulation of nitric oxide biosynthesis
ID: 0045786
Name: negative regulation of progression through cell cycle
ID: 0050730
Name: regulation of peptidyl-tyrosine phosphorylation
ID: 0050999
Name: regulation of nitric-oxide synthase activity
ID: 0051015
Name: actin filament binding
ID: 0051205
Name: protein insertion into membrane

HUGO  Top

ID: EGFR

InterPro  Top

ID: IPR000494
Name: EGFR_L
Description: Epidermal growth-factor receptor (EGFR), L domain
ID: IPR000719
Name: Prot_kinase
Description: Protein kinase
ID: IPR001245
Name: Tyr_pkinase
Description: Tyrosine protein kinase
ID: IPR006211
Name: Furin-like
Description: Furin-like cysteine rich region
ID: IPR008266
Name: Tyr_pkinase_AS
Description: Tyrosine protein kinase, active site

OMIM  Top

ID: 131550

PDB  Top

ID: 1DNQ
ID: 1DNR
ID: 1IVO
ID: 1M14
ID: 1M17
ID: 1MOX
ID: 1NQL
ID: 1XKK

Pfam  Top

ID: PF00069
ID: PF00757
ID: PF01030
ID: PF07714

RefSeq  Top

ID: NP_005219
ID: NP_958439
ID: NP_958440
ID: NP_958441

UniGene  Top

ID: Hs.488293

UniProt  Top

ID: P00533
Symbol: EGFR
Name: EGFR_HUMAN
ID: Q4H1F3
Symbol: EGFR
ID: Q59FL8
Symbol: EGFR
ID: Q68GS5
Symbol: EGFR
ID: Q68GS6
Symbol: EGFR
ID: Q75MF2
Symbol: EGFR
ID: Q8WZA5
Symbol: EGFR
ID: Q9H3C8
Symbol: EGFR

Expression Profile  Top

Gene ID 201983_s_at 201984_s_at 211551_at
H1-ESC percent exp
H2-ESC percent exp
H9-ESC percent exp
Lethality
symbol EGFR EGFR EGFR
CardiacMyocytes      
Heart      
Heart_GSE3585_      
Heart_GSM4467     2.801056
ESC-H1p_      
ESC-H9_     2.902945
ESC_derived-MSC     4.32134
ESC-H2   2.615118  
EBs-H2-14d      
hEBs-H2-5d 5.909365 2.756329 2.736967
CardiacMyocytes-call 0 0 0
Heart-call 0 0 0
Heart_GSE3585-call 0 0 0
Heart_GSM4467-call 0 0 0.222204
atrioventricular_node-call 0 0 0.575005
ESC-H1-call 0 0 0
ESC-H2-call 0 0.9067578 0
ESC-H9-call 0 0 0.2384644
GPCR-sing ling-component      
GPCR      
Phenotype_full adipose tissue|cardiovascular system|craniofacial| adipose tissue|cardiovascular system|craniofacial| adipose tissue|cardiovascular system|craniofacial|
Phenotype lethality-embryonic|heart lethality-embryonic|heart lethality-embryonic|heart
expressed P-call_max2 1 1 1
Notes      
  Top